Unexpected glutamatergic excitatory axon terminals (dark green) from the ventral tegmental area make synaptic contacts on a dendrite of a parvalbumin neuron (magenta) involved in aversion. From art view, all kind of cellular organelle at ultrastructural level look like diverse groups of sea animals sadly jumping out of the contaminated river. They are not happy and rewarding! Image by Shiliang (Steven) Zhang (NIH/NIDA)
Human embryonic stem cells, differentiated to cortical neurons and stained with mouse monoclonal antibody against ßIII-tubulin (TUJ1, Covance), a neuronal specific marker, which was detected with goat anti-mouse Alexa 488. The nuclei were counterstained with DAPI and the image pseudo-colored with red. The merge shows neurons in green and the nuclei in yellow. Image by C. Kaneski (NIDDK/NIH)